Principal Investigator

Athanassios Sambanis, Ph.D.

Professor, School of Chemical & Biomolecular Engineering

 

Education

B.S. Chemical Engineering (1979),

             National Technical University, Athens, Greece

Ph.D. Chemical Engineering (1985),

             University of Minnesota, Minneapolis, Minnesota

Post-Doctoral training at the Biotechnology Process Engineering Center (1987-1989),

             Massachusetts Institute of Technology

Post-Doctoral Associates

Kiran Durvasula, Ph.D.

Post-Doctoral Associate

 

Research Interests

Genetic engineering of non-beta cells for insulin secretion; characterization of insulin secretion kinetics; mathematical modeling of insulin biosynthesis and intracellular trafficking.

Graduate Students

Hajira Ahmad

Ph.D. Candidate, Wallace H. Coulter Department of Biomedical Engineering

 

Research Interests

Encapsulated cell cryopreservation; studies on cellular metabolism by 13C labeling and isotopomeric analysis; development of hydrogel matrices for adherent cells.

 

Alison Lawson

Ph.D. Candidate, School of Chemical & Biomolecular Engineering

 

Research Interests

Encapsulated cell cryopreservation; mathematical modeling of cryoprotectant delivery and removal; in vitro and in vivo assessment of encapsulated cell function post-cryopreservation.

 

Fernie Goh

Ph.D. Candidate, School of Chemical & Biomolecular Engineering

 

Research Interests

Incorporation of perfluorocarbons (PFCs) in encapsulated cell systems; characterization of such systems experimentally and by mathematical modeling; non-invasive monitoring of capsules in vitro and in vivo by 19F NMR.

 

Saif Al-Mamari

Ph.D. Candidate, School of Chemical & Biomolecular Engineering

 

Research Interests

Bioreactors for porcine islet culturing; secretion studies on free and encapsulated islets in vitro and after various periods of in vivo implantation.

 

Stephanie Duncanson

Ph.D. Candidate, Bioengineering Program, School of Chemical & Biomolecular Engineering

 

Research Interests

Incrorporation of chemorepellents in encapsulation matrices; development of spheroid cultures of cells for improved incorporation in encapsulation devices.

 

Aubrey Tiernan

Ph.D. Candidate, School of Chemical & Biomolecular Engineering

 

Research Interests

Genetic engineering of cells for insulin secretion, cell encapsulation.

Undergraduate Students

Chun Yong

Undergraduate Research Scholar, Wallace H. Coulter Department of Biomedical Engineering

Graduate Mentor: Alison Lawson

 

Research Interests

Mechanical properties and permeability of encapsulation matrices in vitro and after various periods of in vivo implantation; development of in vitro culture systems simulating the in vivo environment.

 

David Detwiler

Undergraduate Research Assistant, School of Chemical & Biomolecular Engineering

 

Research Interests

Bioreactors for perifusion studies; measurements on insulin secretion kinetics by perifusion.