Publications

1. Sambanis, A., “Artificial Organs: Pancreas” in Comprehensive Biotechnology, Volume 5:   Medical Biotechnology and Healthcare, Elsevier (in press).

2. Bara H., Thulé P.M. and Sambanis A., “A Cell-Based Approach for Diabetes Treatment Using Engineered non-β Cells,” Journal of Diabetes Science and Technology, 3: 555-561 (2009).

3. Bara H. and Sambanis A., “Development and Characterization of a Tissue Engineered Pancreatic Substitute Based on Recombinant Intestinal Endocrine L-Cells,” Biotechnology and Bioengineering, 103: 828-834 (2009).

4. Bara H. and Sambanis A., “Insulin-secreting L-cells for the Treatment of Insulin Dependent Diabetes,” Biochem Biophys Res Commun, 371: 39-43 (2008).

5. Gross, J.D., Long, R.C., Jr., Constantinidis, I., and Sambanis, A., “Monitoring of Dissolved Oxygen and Cellular Bioenergetics within a Pancreatic Substitute,” Biotechnology and Bioengineering, 98: 261-270 (2007).

6. Mukherjee, I.N., Song, Y. C., and Sambanis, A., “Cryoprotectant Delivery and Removal from Murine Insulinomas at Vitrification-Relevant Concentrations,” Cryobiology, 55: 10-18 (2007).

7. Bartling, K., Sambanis, A., and Rousseau, R.W., “Dependence of Apoferritin Crystal Growth on Temperature and Cadmium Concentration,” Crystal Growth and Design, 7: 569-575 (2007).

8. Gross, J.D., Constantinidis, I., and Sambanis, A., “Modeling of Encapsulated Cell Systems,” Journal of Theoretical Biology, 244: 500-510 (2007).

9. Sambanis, A., “Bioartificial Pancreas,” in "Principles of Tissue Engineering” 3rd Edition (Lanza R., Langer R. and Vacanti J., Editors), pp 619-630, Elsevier/ Academic Press (2007).

10. Constantinidis, I., Simpson, N.E., Grant, S.C., Blackband, S.J., Long, R.C., Jr. and Sambanis, A., “Non-Invasive Monitoring of Tissue-Engineered Pancreatic Constructs by NMR Techniques,” Advances in Experimental Medicine and Biology, 585: 261-276 (2006).

11. Cheng, S-Y, Constantinidis, I. and Sambanis, A., “Insulin Secretion Dynamics of Free and Alginate-Encapsulated Insulinoma Cells,” Cytotechnology, 51: 159-170 (2006).

12. Cheng, S-Y., Constantinidis, I. and Sambanis, A., “Use of Glucose-Responsive Material to Regulate Insulin Release from Constitutively Secreting Cells,” Biotechnology and Bioengineering, 93: 1079-1088 (2006).

13. Bartling, K., Sambanis, A. and Rousseau, R.W., “Multiwell Microbatch Crystallization on a Thermal Gradient,” Crystal Growth and Design, 5: 1559-1564 (2005).

14. Mukherjee, I.N., Song, Y. C., Chen, Z.Z. and Sambanis, A., “Effects of Cryopreservation on Cell Viability and Insulin Secretion in a Model Tissue Engineered Pancreatic Substitute,” Cell Transplantation, 14: 449-456 (2005)

15. Berglund, J.D., Nerem, R.M., and Sambanis, A., “Viscoelastic Testing Methodologies for Tissue Engineered Blood Vessels,” Journal of Biomechanical Engineering, 127: 1176-1184 (2005).

16. Tang, S-C., Sambanis, A. and Sibley, E., “Enhancement of Recombinant Adeno-Associated Virus 2 (rAAV2) Transduction of Intestinal Epithelial Cells via Proteasome Modulating Agents,” Biochem Biophys Res Commun., 331:  1392-1400 (2005)

17. Song, Y.C., Chen, Z.Z., Mukherjee, N., Lightfoot, F.G., Taylor, M.J., Brockbank, K.G. and Sambanis, A., “Vitrification of tissue engineered pancreatic substitute,” Transplantation Proceedings, 37: 253-255 (2005)

18. Stabler, C.L., Long, R.C., Jr., Sambanis, A., and Constantinidis, I., “Noninvasive Measurement of Viable Cell Number in Tissue Engineered Constructs In Vitro using 1H NMR Spectroscopy,” Tissue Engineering, 11: 404-414 (2005).

19. Stabler, C.L., Long, R.C., Jr., Constantinidis, I. and Sambanis, A., “In Vivo Noninvasive Monitoring of a Tissue Engineered Construct Using 1H NMR Spectroscopy,” Cell Transplantation, 14: 139-149 (2005).

20. Oca-Cossio, J., Mao, H., Khokhlova, N., Kennedy, C.M., Kennedy, J.W., Stabler, C.L., Hao, E., Sambanis, A., Simpson, N.E., and Constantinidis, I., “Magnetically Labeled Insulin-Secreting Cells,” Biochem. Biophys. Res. Commun., 319: 569-575 (2004).

21. Berglund, J.D., Nerem, R.M., and Sambanis, A., “Incorporation of Intact Elastin Scaffolds in Tissue Engineered Collagen-Based Vascular Grafts,” Tissue Engineering, 10: 1526-1535 (2004).

22. Tang, S-C. and Sambanis, A., “Differential rAAV2 Transduction Efficiencies and Insulin Secretion Profiles in Pure and Co-Culture Models of Human Enteroendocrine L-Cells and Enterocytes,” The Journal of Gene Medicine, 6: 1003-1013 (2004).

23. Cheng, S-Y., Gross, J., and Sambanis, A., “Hybrid Pancreatic Tissue Substitute Consisting of Recombinant Insulin-Secreting Cells and Glucose-Responsive Material,” Biotechnol. Bioeng., 87: 863-873 (2004).

24. Simpson, N.E., Stabler, C.L., Simpson, C.P., Sambanis, A., and Constantinidis, I., “The Role of the CaCl2-Guluronic Acid Interaction on Alginate Encapsulated βTC3 Cells,” Biomaterials, 25: 2603-2610 (2004).

25. Sambanis, A., “Encapsulated Islets in Diabetes Treatment,” Diabetes Technology and Therapeutics, 5: 665-668 (2003).

26. Tang, S-C. and Sambanis, A., “Development of Genetically Engineered Human Intestinal Cells for Regulated Insulin Secretion Using rAAV-Mediated Gene Transfer,” Biochem. Biophys. Res. Commun., 303: 645-652 (2003).

27. Tang, S-C., and Sambanis, A., “Preproinsulin mRNA Engineering and its Application to the Regulation of Insulin Secretion from Human Hepatomas,” FEBS Letters, 537: 193-197 (2003).

28. Berglund, J.D., Mohseni, M.M., Nerem, R.M., and Sambanis, A., “A Biological Hybrid Model for Collagen-based Tissue Engineered Vascular Constructs,” Biomaterials, 24: 1241 – 1254 (2003).

29. Constantinidis, I., Stabler, C.L., Long, R.C., Jr., and Sambanis, A., “Noninvasive Monitoring of a Retrievable Bioartificial Pancreas in vivo,” Ann. N Y Acad. Sci. 961:  298-301 (2002).

30. Stabler, C. L., Sambanis, A., and Constantinidis, I., “Effects of Alginate Composition on the Growth and Overall Metabolic Activity of betaTC3 Cells,” Ann. N Y Acad. Sci. 961:  130-133 (2002).

31. Sambanis, A., Tang, S.-C., Cheng, S.-Y., Stabler, C.L., Long, R.C. Jr., and Constantinidis, I., “Core Technologies in Tissue Engineering and their Application to the Bioartificial Pancreas,” in Tissue Engineering for Therapeutic Use 6, (Ikada Y., Umakoshi, Y. and Hotta T. Editors), pp. 5-18, Elsevier, Boston MA (2002).

32. Cui, Z.F., Dykhuizen, R.C., Nerem, R.M., and Sambanis, A., “Modeling of Cryopreservation of Engineered Tissues with One-Dimensional Geometry,” Biotechnol. Progress 18: 354-361 (2002).

33. Abruzzo, T., Cloft, H.J., Marek, M., Shengelaia, G.G., Snowhill, P.B., Miller Waldrop, S., and Sambanis, A., “Interaction of Vascular Smooth Muscle Cells with Collagen-Impregnated Embolization Coils Studied with a Novel Quantitative In Vitro Model,” American Journal of Neuroradiology, 23: 674-681 (2002).

34. Constantinidis, I., Long, R.C., Jr., Weber, C., Safley, S. and Sambanis, A., “Non-Invasive Monitoring of a Bioartificial Pancreas In Vitro and In Vivo”, Annals of the New York Academy of Sciences, 944: 83-95 (2001).

35. Murphy, C.L. and Sambanis, A., “Effect of Oxygen Tension and Alginate Encapsulation on Restoration of the Differentiated Phenotype of Passaged Chondrocytes,” Tissue Engineering, 7: 791-803 (2001).

36. Constantinidis, I., Grant, S.C., Simpson, N.E., Oca-Cossio, J.A., Sweeney, C.A., Mao, H.,  Blackband, S.J. and Sambanis, A., “Use of Magnetic Nanoparticles to Monitor Alginate-Encapsulated βTC-tet Cells,” Magnetic Resonance in Medicine, 61: 282-290 (2009).

37. Mukherjee, I.N., Li, Y., Song, Y.C., Long, R.C. Jr., and Sambanis, A., “Cryoprotectant Transport through Articular Cartilage for Long-Term Storage: Experimental and Modeling Studies,” Osteoarthritis and Cartilage, 16: 1379-1386 (2008) (epub date 2008/06/10).

38. Murphy, C.L. and Sambanis, A., “Effect of Oxygen Tension on Chondrocyte Extracellular Matrix Deposition,” Connective Tissue Research, 42: 87-96 (2001).

39. Abruzzo, T., Cloft, H.J., Shengelaia, G.G., Waldrop, S.M., Kallmes, D.F., Dion, J.E., Constantinidis, I. and Sambanis, A., “In vitro effects of transcatheter injection on structure, cell viability, and cell metabolism in fibroblast-impregnated alginate microspheres,” Radiology, 220: 428-435 (2001).

40. Paxton, T.E., Sambanis, A., and Rousseau, R.W. “Influence of Vessel Surfaces on the Nucleation of Protein Crystals,” Langmuir, 17: 3076-3079 (2001).

41. Stabler, C., Wilks, K., Sambanis, A. and Constantinidis, I., “The Effects of Alginate Composition on Encapsulated bTC3 Cells,” Biomaterials, 22: 1301-1310 (2001).

42. Long, R.C., Jr., Papas, K.K., Sambanis, A. and Constantinidis, I., “In Vitro Monitoring of Total Choline Levels in a Bioartificial Pancreas:  1H NMR Spectroscopic Studies of the Effects of Oxygen Level,” Journal of Magnetic Resonance, 146: 49-57 (2000).

43. Papas, K.K., Long, R.C., Jr., Constantinidis, I. and Sambanis, A., “Effects of Short-Term Hypoxia on a Bioartificial Pancreatic Construct,” Cell Transplantation, 9: 415-422 (2000).

44. Simpson, N.E., Bennett, L.K., Papas, K.K., Sambanis, A., and Constantinidis, I., “Effects of pH on Murine Insulinoma bTC3 Cells,” Biochem. Biophys. Research Commun., 273: 937-941 (2000).

45. Sambanis, A., “Engineering Challenges in the Development of an Encapsulated Cell System for Treatment of Type I Diabetes,” Diabetes Technology and Therapeutics, 2: 81-89 (2000).